Clinical trials and ongoing research

Our Ongoing Research Projects

Calmino has been a partner in several clinical trials including over 200 participants. Our current ongoing clinical study aims at analysing the Effects of chemically characterized Aloe barbadensis Mill. extract on gastrointestinal function, fecal microbiota and fecal metabolite composition in healthy adults in a randomized, double-blind, placebo-controlled study. The study is currently recruiting participants and is aimed for completion in 2021.

Other Ongoing Research Projects Include
  • Describing the intestinal microenvironment, combining fecal microbiota and metabolite profiles, in IBS patients (all subtypes) and healthy subjects, and its association to symptoms related to IBS.
  • Comparing the immunosuppressive effect of various Aloe vera extracts (in vitro) and a comprehensive analysis of their bioactive composition.
  • Effect of Aloe vera extract intervention on IBS symptom severity in various IBS subgroups based on bowel habits